Avantor Inc

Item 1A. Risk factors

For information regarding factors that could affect the Company's results of operations, financial condition and liquidity, see the risk factors discussed in Part I, Item 1A Risk Factors in our Annual Report andfor the following risk factor, which supplements and should be read in conjunction with the risk factors discussed inyear ended December 31, 2024, as supplemented by Part II, Item 1A Risk Factors in our Annual Report.

Changes to trade policy, including new or increased tariffs and changing imQuarterly Report/export regulations, may adversely affect our business, financial condition and results of operations.

Changes in U.S. or in on Form 10-Q for the quarternational laws and policies governing foreign trade could materially and adversely affect our businessly period ended March 31, 2025. The U.S. has instituted certain changes, and has proposed additionre have been no material changes, in trade policies to that include the negotiation or termination of trade agreements, the imposition of higher tariffs on

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imports into the U.S., ane risk factors d other government regulations affecting trade between the U.S. and other countries where we conduct our business. The new tariffs and other changes in U.S. trade policy have triggered retaliatory actions by affected countries, and foreign governments have instituted or are considering imposing trade sanctions on U.S. goods.

The imposition of tariffs and otheisclosed in Part I, Item 1A Risk Factors in our Annual Report for trade restrictions, as well as the escalation of trade disputes and any downturns in the global economy resulting therefrom, could materially and adversely affect our business, financial condition and results of operations. The extent and duration of the tariffs and other trade restrictions and the resulting impact on general economic conditions and on our business are uncertain and depend on various factors, such as negotiations between the U.S. and affected countries, the responses of other countries or regions, exemptions or exclusions that may be granted, availability and cost of alternative sources of supply, and demand for our products in affected markets.

Further, actions we take to adapt to new tariffs year ended December 31, 2024, as supplemented by Part II, Item 1A Risk Factors in our Quarterly Report on Form 10-Q for other trade restrictions may cause us to modify our o quarterly perations, which could be time-consuming and expensive, impact pricing of our products, which could impact our sales and profitability, or cause us to forgo business opportunitiesiod ended March 31, 2025.